Anti-typhoid Activity of Adhatoda vasica and Vitex negundo

Persian Gulf Crop Protection

Available online on: www.cropprotection.ir

ISSN: 2251-9343 (Online)

Volume 2 Issue 3, September 2013

Pages 64-75

Anti-typhoid Activity of Adhatoda vasica and Vitex negundo

Manoj Kumar1*, Sukumar Dandapat1, Amit Kumar1 and M. P. Sinha1

1-Department of Zoology, Ranchi University, Ranchi, India (*Corresponding author e-mail:eaddress.manojkumar@gmail.com).

Abstract: Typhoid activity is an acute systemic infection caused by Salmonella typhi. In present study

the methanolic leafs extract of Vitex negundo and Adhatoda vasica were analyzed for anti-typhoid

activity against Salmonella typhi. The leave sample was subjected to phytochemical analysis. The

concentration of all the phytochemicals studied was higher in Vitex negundo than Adhatoda vasica,

except alkaloids which was higher in Adhatoda vasica (11.3 ± 0.1mg/g) than Vitex negundo (8.6 ± 0.00

mg/g). Tannins were highest in both the plants, 61.3 ± 0.8 mg/g in Adhatoda vasica and 93.9 ± 0.8

mg/g in Adhatoda vasica. The antioxidant activity was determined and compared with BHA and

reducing power was compared with Ascorbic acid. Both the samples had high antioxidant and reducing

power activity. Several studies reported the loss of antioxidant system during infection of Salmonella

typhi. The leaf extracts of Adhatoda vasica and Vitex negundo showed considerable antioxidant activity

which can used as remedy against antioxidant system collapse and thus promises to be effective

antioxidant supplement for typhoid patients. Besides antioxidant activity the leaves of both plants

inhibited the growth of Salmonella typhi. The antibacterial activity of both leaf extracts were compared

with gentamycin. The results of present study shows that leaf extracts of Vitex negundo and Adhatoda vasica

confer anti-typhoid activity against Salmonella typhi.

Key Words: Anti-typhoid, Adhatoda vasica, Vitex negundo.

Determination of Nutritive Value and Mineral Elements of Five-Leaf Chaste Tree (Vitex negundo L.) And Malabar Nut (Adhatoda vasica Nees)

Academic Journal of Plant Sciences 6 (3): 103-108, 2013
ISSN 1995-8986
© IDOSI Publications, 2013
DOI: 10.5829/idosi.ajps.2013.6.3.11011

Determination of Nutritive Value and Mineral Elements of

Five-Leaf Chaste Tree (Vitex negundo L.) And Malabar Nut

(Adhatoda vasica Nees)

Manoj Kumar*, Sukumar Dandapat, Amit Kumar and M.P. Sinha

Department of Zoology, Ranchi University, Ranchi - 834008, India.

Abstract: 

This study was undertaken to assess the nutritive value and mineral contents from Vitex negundo and Adhatoda vasica. These two plant species are fairly used as medicine throughout the greater part of India. Adhatoda vasica is used to control pain, inflammation and other related diseases. Leaves of Adhatoda vasica are used for treatment of cold, cough, chronic bronchitis and asthma. It was also used by traditional midwives at the time of delivery. The leaves of Adhatoda vasica are extensively used in indigenous medicines remedies. Both the plants contained important macro and micro elements: K, Ca, Fe, Cu, Zn and Cr. These elements were found in more quantity in Vitex negundo than in Adhatoda vasica. The leaves of both the plants were analyzed for ash content, moisture, crude fat, crude fibre, crude carbohydrate and crude protein content. The results for percentage of ash content, moisture content, crude fat, crude fiber, carbohydrate and protein were 5.4 ± 0.35, 16.50 ± 1.2, 7 ± 0.7, 28.02 +1.03, 8.5 ± 0.45, 13.7 ± 1.04 % respectively for Vitex negundo; and 5.2 ± 1.23, 15.3 ± 0.5, 1.6 ± 0.3, 6.4 ± 0.45, 16.4 ± 0.8, 6.5 ± 0.3 respectively for Adhatoda vasica. The leaves were also assessed for nutritional value. Nutritional value of Vitex negundo was 151.80 Cal/100g and that of Adhatoda vasica was 106.00 Cal/100.g.

Key words:

Vitex negundo, Adhatoda vasica, Nutritive value, Mineral contents

Corresponding Author: Manoj Kumar, Department of Zoology, Ranchi University, Ranchi - 834008, India.

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