MANOJ KUMAR (SHELFORD)

Wednesday, July 9, 2014

Pharmacological Screening of Leaf Extract of Adhatoda vasica for Therapeutic Efficacy

ISSN 1992-0075
DOI: 10.5829/idosi.gjp.2014.8.4.8419



ManojKumar, Sukumar Dandapat, Amit Kumar and M.P. Sinha




Abstract: In the present study Adhatoda vasica was screened for therapeutic efficacy. The plant leaf extract was screened for phytochemicals, mineral elements, antioxidant and reducing power activity, foaming and swelling index properties. Both qualitative and quantitative analyses of phytochemicals were done. The result showed the presence of alkaloids, tannins, saponins, phenolics and flavonoids. Tannins were maximum among all the detected phytochemicals (61.38 ± 0.8 mg/g). Phenolics were minimum (1.30 ± 0.1 mg/g). Following the presence of phytochemicals the plant leaf samples were also screened for antioxidant and reducing power ability. The screening for mineral elements revealed the presence of macro and micro elements. Potassium (K), Calcium (Ca), iron (Fe), Copper (Cu), Zinc (Zn), Chromium (Cr), Vanadium and Manganese (Mn) were detected in the leaf sample. Adhatoda vasica showed highest (68070 ± 35.58 ppm) concentration of Ca. V was lowest among all the mineral elements (118 ± 6.03 pm). Since the plant contains important phytochemicals, mineral elements, antioxidant and reducing power analysis, it may be good source of future medicines.


 

Key words: Phytochemicals,  Mineral Elements, Antioxidant, Reducing Power


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